A Microsoft App-V developer specializes in creating, managing, and deploying virtual applications using Microsoft's Application Virtualization (App-V) technology. They encapsulate applications from the OS, enabling them to run in a self-contained virtual environment on any computer. This mitigates application conflicts and testing requirements, enhancing flexibility. They also handle version control and roll-out updates without disrupting the user. Moreover, they troubleshoot issues related to virtual applications, ensuring smooth operations. Their role involves close collaboration with IT teams for integrating App-V into systems infrastructure, enhancing the overall software deployment process.